Knowing the protein structure became crucial for life sciences these days. Our new, unique technology called Protein Tomography enables effective drug discovery by revealing critical information at early stages of drug development. It allows visualization of protein structures at the individual, single molecule level in short time with high accuracy.
Our technology is a unique combination of Cryo Electron Microscopy and specifically design 3D reconstruction program called COMET (Constrained Maximum Entropy Tomography), which innovative algorithms enhance resolution, producing noise free reconstructions of target proteins. Depending on customer’s needs we can produce different kind of images, from multiple tilted views from a specimen for 3D tomograms (individual molecule visualization) to a large number of 2D images (for averaged reconstructions).
The new technology allows visualization of protein complexes and their dynamics, serving as an alternative solution to the study of biological samples that are difficult or impossible to crystallize. Proteins that with conventional methods were unable to visualize, are now easily reconstructed with our service.